STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PTCH2LOW QUALITY PROTEIN: protein patched homolog 2. (1293 aa)    
Predicted Functional Partners:
SHH
Sonic hedgehog protein.
   
 0.984
IHH
Indian hedgehog protein.
   
 0.983
DHH
LOW QUALITY PROTEIN: desert hedgehog protein.
   
 0.982
BOC
Brother of CDO isoform X2.
    
 0.977
CDON
Cell adhesion molecule-related/down-regulated by oncogenes.
    
 0.977
SMURF1
E3 ubiquitin-protein ligase SMURF1 isoform X1.
    
 0.968
SMURF2
E3 ubiquitin-protein ligase SMURF2.
    
 0.968
SMO
Smoothened, frizzled class receptor.
    
 0.945
PTCH1
Patched 1.
  
  
 
0.908
LRP2
Low-density lipoprotein receptor-related protein 2.
    
 0.908
Your Current Organism:
Serinus canaria
NCBI taxonomy Id: 9135
Other names: Atlantic canary, Canario raza, Common canary, S. canaria, Serinus canarius, canary
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.