Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CISHCytokine inducible SH2-containing protein. (257 aa)    
Predicted Functional Partners:
CUL5
Cullin 5.
   
 0.965
ELOC
Elongin-C.
    
 0.832
SOCS5
Suppressor of cytokine signaling 5.
     
0.804
SOCS4
Suppressor of cytokine signaling 4.
     
0.803
SOCS2
Suppressor of cytokine signaling 2.
   
 
0.793
SOCS3
Suppressor of cytokine signaling 3.
   
 
0.768
SOCS6
Suppressor of cytokine signaling 6/7.
     
0.759
RNF7
RING-box protein 2 isoform X1.
   
 0.751
SPSB3
SPRY domain-containing SOCS box protein 3 isoform X1.
     
 0.702
SERPINC1
Antithrombin III.
      
 0.695
Your Current Organism:
Serinus canaria
NCBI taxonomy Id: 9135
Other names: Atlantic canary, Canario raza, Common canary, S. canaria, Serinus canarius, canary
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