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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CD38ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 isoform X1. (308 aa)    
Predicted Functional Partners:
NADK
NAD kinase isoform X1.
     
 0.944
NAMPT
Nicotinamide phosphoribosyltransferase isoform X1.
     
 0.905
BST1
ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 2 isoform X1.
  
  
 
0.904
SIRT1
NAD-dependent protein deacetylase sirtuin-1 isoform X2.
     
 0.902
NMNAT3
Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 3 isoform X3.
     
 0.901
SIRT5
NAD-dependent protein deacylase sirtuin-5, mitochondrial isoform X1.
     
 0.900
SIRT4
NAD-dependent protein lipoamidase sirtuin-4, mitochondrial.
     
  0.900
TPCN1
Two pore calcium channel protein 1 isoform X2.
     
  0.900
PNP
Purine nucleoside phosphorylase.
     
  0.900
RYR2
Ryanodine receptor 2.
     
  0.900
Your Current Organism:
Serinus canaria
NCBI taxonomy Id: 9135
Other names: Atlantic canary, Canario raza, Common canary, S. canaria, Serinus canarius, canary
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