STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TP73Tumor protein p73 isoform X1. (650 aa)    
Predicted Functional Partners:
ITCH
E3 ubiquitin-protein ligase Itchy homolog.
    
 0.971
MDM2
E3 ubiquitin-protein ligase Mdm2.
    
 0.967
TP63
Tumor protein 63 isoform X2.
    
 0.967
YAP1
Yes associated protein 1.
    
 0.947
EP300
Histone acetyltransferase p300.
    
 0.947
MDM4
Protein Mdm4.
    
 0.932
RPS27A
Ubiquitin-small subunit ribosomal protein S27Ae.
    
  0.845
WRN
Werner syndrome ATP-dependent helicase isoform X2.
    
 0.842
WWOX
WW domain-containing oxidoreductase.
    
 
 0.831
IL10RB
Interleukin-10 receptor subunit beta.
    
 0.814
Your Current Organism:
Serinus canaria
NCBI taxonomy Id: 9135
Other names: Atlantic canary, Canario raza, Common canary, S. canaria, Serinus canarius, canary
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.