STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
JAK2Tyrosine-protein kinase JAK2. (1130 aa)    
Predicted Functional Partners:
STAT3
Signal transducer and activator of transcription 3 isoform X2.
   
 0.999
IFNGR2
Interferon gamma receptor 2.
    
 0.998
SOCS3
Suppressor of cytokine signaling 3.
   
 0.997
GHR
Growth hormone receptor.
    
 0.996
STAT1
Signal transducer and activator of transcription 1-alpha/beta.
   
 0.994
PTPN11
Tyrosine-protein phosphatase non-receptor type 11.
   
 0.994
LEPR
Leptin receptor.
    
 0.990
IFNGR1
Interferon gamma receptor 1 isoform X1.
   
 0.987
LOC103821589
Signal transducer and activator of transcription 5B isoform X1.
   
 0.987
IFNAR1
Interferon alpha/beta receptor 1.
   
 0.975
Your Current Organism:
Serinus canaria
NCBI taxonomy Id: 9135
Other names: Atlantic canary, Canario raza, Common canary, S. canaria, Serinus canarius, canary
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.