Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
NPHP4Nephrocystin-4 isoform X2. (1163 aa)    
Predicted Functional Partners:
NPHP1
Nephrocystin 1.
   
 0.977
LOC103816470
Protein fantom.
    
 0.973
RPGR
X-linked retinitis pigmentosa GTPase regulator.
   
 
 0.847
LATS1
Serine/threonine-protein kinase LATS1 isoform X2.
    
 0.650
LATS2
Serine/threonine-protein kinase LATS1/2.
    
  0.622
FMNL2
LOW QUALITY PROTEIN: formin-like protein 2.
    
 0.614
FMNL1
Formin like 1.
    
 0.614
ENSSCAP00000019160
annotation not available
    
 0.614
IQCB1
IQ calmodulin-binding motif-containing protein 1 isoform X1.
    
 
 0.613
TMEM67
Meckelin.
   
  
 0.595
Your Current Organism:
Serinus canaria
NCBI taxonomy Id: 9135
Other names: Atlantic canary, Canario raza, Common canary, S. canaria, Serinus canarius, canary
Server load: low (16%) [HD]