Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
GLIS3Zinc finger protein GLIS1/3. (765 aa)    
Predicted Functional Partners:
SUFU
SUFU negative regulator of hedgehog signaling.
    
 0.942
SMO
Smoothened, frizzled class receptor.
    
 0.774
SPOP
Speckle-type POZ protein isoform X1.
   
 0.754
SPOPL
Speckle-type POZ protein-like.
   
 0.754
STK36
Serine/threonine kinase 36.
    
 0.710
CSNK1A1
Casein kinase I isoform X1.
    
 0.663
GSK3B
Glycogen synthase kinase-3 beta isoform X1.
   
 0.654
PTCH2
LOW QUALITY PROTEIN: protein patched homolog 2.
   
 0.650
PTCH1
Patched 1.
   
 0.650
KIF27
Kinesin family member 27.
    
 0.635
Your Current Organism:
Serinus canaria
NCBI taxonomy Id: 9135
Other names: Atlantic canary, Canario raza, Common canary, S. canaria, Serinus canarius, canary
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