Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
TJP2Tight junction protein ZO-2 isoform X1. (1162 aa)    
Predicted Functional Partners:
TJP1
Tight junction protein ZO-1 isoform X1.
   
0.990
AFDN
Afadin, adherens junction formation factor.
   
 0.979
ENSSCAP00000006847
Uncharacterized protein LOC103824942.
   
 0.965
YAP1
Yes associated protein 1.
   
 0.943
RAPGEF2
Rap guanine nucleotide exchange factor 2 isoform X4.
     
 0.908
NR1H4
Bile acid receptor isoform X2.
      
 0.873
GJA1
Gap junction alpha-1 protein.
   
 0.783
ATP8B1
Phospholipid-transporting ATPase IC.
      
 0.769
CLDN3
Claudin-3.
   
 
 0.707
FAM189A2
Protein FAM189A2.
    
 
 0.689
Your Current Organism:
Serinus canaria
NCBI taxonomy Id: 9135
Other names: Atlantic canary, Canario raza, Common canary, S. canaria, Serinus canarius, canary
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