STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MLANAmelan-A. (112 aa)    
Predicted Functional Partners:
DCT
L-dopachrome tautomerase.
   
  
 0.887
GPR143
G-protein coupled receptor 143.
   
 
 0.802
SLC24A5
Solute carrier family 24 (sodium/potassium/calcium exchanger), member 5.
   
  
 0.684
MITF
Melanocyte inducing transcription factor.
    
 0.669
TYR
Tyrosinase.
      
 0.612
TYRP1
LOW QUALITY PROTEIN: 5,6-dihydroxyindole-2-carboxylic acid oxidase.
      
 0.602
ITCH
E3 ubiquitin-protein ligase Itchy homolog.
    
   0.594
OCA2
P protein.
   
  
 0.565
SLC45A2
Membrane-associated transporter protein isoform X2.
   
  
 0.530
SLC45A1
Proton-associated sugar transporter A isoform X1.
   
  
 0.530
Your Current Organism:
Serinus canaria
NCBI taxonomy Id: 9135
Other names: Atlantic canary, Canario raza, Common canary, S. canaria, Serinus canarius, canary
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.