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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PPARGC1BPPARG coactivator 1 beta. (958 aa)    
Predicted Functional Partners:
MED15
Mediator complex subunit 15.
     
 0.829
MED19
Mediator complex subunit 19.
     
 0.817
MED13
Mediator of RNA polymerase II transcription subunit 13.
     
 0.815
MED13L
Mediator of RNA polymerase II transcription subunit 13-like isoform X1.
     
 0.810
MED1
LOW QUALITY PROTEIN: mediator of RNA polymerase II transcription subunit 1.
     
 0.808
NRF1
LOW QUALITY PROTEIN: nuclear respiratory factor 1.
     
 0.802
MED27
Mediator of RNA polymerase II transcription subunit 27.
     
 0.722
NCBP1
Nuclear cap-binding protein subunit 1.
    
   0.719
MED23
Mediator of RNA polymerase II transcription subunit 23 isoform X1.
     
 0.609
PPARG
Peroxisome proliferator-activated receptor gamma.
    
 0.596
Your Current Organism:
Serinus canaria
NCBI taxonomy Id: 9135
Other names: Atlantic canary, Canario raza, Common canary, S. canaria, Serinus canarius, canary
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.