Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
RNF186E3 ubiquitin-protein ligase RNF186. (218 aa)    
Predicted Functional Partners:
RNF182
E3 ubiquitin-protein ligase RNF182.
      
 0.682
RNF150
RING finger protein 150.
    
 0.682
PLA2G2E
Basic phospholipase A2 caudoxin.
      
 0.596
OTUD3
OTU domain-containing protein 3.
      
 0.580
RNF13
E3 ubiquitin-protein ligase RNF13.
      
 0.528
SVOPL
Putative transporter SVOPL isoform X3.
      
 0.528
PUS10
Putative tRNA pseudouridine synthase Pus10 isoform X3.
      
 0.526
UBE2H
Ubiquitin conjugating enzyme E2 H.
    
 
 0.509
RNF121
Ring finger protein 121.
      
 0.432
RNF103
E3 ubiquitin-protein ligase RNF103 isoform X1.
    
 0.420
Your Current Organism:
Serinus canaria
NCBI taxonomy Id: 9135
Other names: Atlantic canary, Canario raza, Common canary, S. canaria, Serinus canarius, canary
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.