Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
TMCO4Transmembrane and coiled-coil domain-containing protein 4. (609 aa)    
Predicted Functional Partners:
C2CD2L
Phospholipid transfer protein C2CD2L isoform X1.
      
 0.882
C2CD2
C2 calcium dependent domain containing 2.
      
 0.845
RAB3GAP2
Rab3 GTPase-activating protein non-catalytic subunit.
      
 0.769
SEC22A
Vesicle-trafficking protein SEC22a isoform X1.
      
 0.769
TRAPPC9
Trafficking protein particle complex subunit 9 isoform X1.
      
 0.747
SEC22C
SEC22 vesicle trafficking protein A/C.
      
 0.566
INPP5B
Type II inositol 1,4,5-trisphosphate 5-phosphatase.
      
 0.532
AP1B1
Adaptor related protein complex 1 subunit beta 1.
    
 
 0.491
AP2B1
AP-2 complex subunit beta isoform X1.
    
 
 0.491
AP4B1
LOW QUALITY PROTEIN: AP-4 complex subunit beta-1.
    
 
 0.491
Your Current Organism:
Serinus canaria
NCBI taxonomy Id: 9135
Other names: Atlantic canary, Canario raza, Common canary, S. canaria, Serinus canarius, canary
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