Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
SH3GL2Endophilin-A1. (337 aa)    
Predicted Functional Partners:
SH3KBP1
SH3 domain-containing kinase-binding protein 1 isoform X1.
   
 
0.923
CBL
E3 ubiquitin-protein ligase CBL.
    
  0.874
CBLB
E3 ubiquitin-protein ligase CBL-B isoform X1.
    
  0.874
SYNJ1
Synaptojanin-1 isoform X1.
    
 
 0.829
EGFR
Epidermal growth factor receptor isoform X3.
    
 0.818
DNM3
LOW QUALITY PROTEIN: dynamin-3.
   
 0.795
DNM1
Dynamin-1 isoform X4.
   
 0.795
GAK
Cyclin-G-associated kinase isoform X1.
   
 0.780
DNM1L
Dynamin-1-like protein isoform X1.
   
 0.743
SYNJ2
Synaptojanin-2.
    
 
 0.708
Your Current Organism:
Serinus canaria
NCBI taxonomy Id: 9135
Other names: Atlantic canary, Canario raza, Common canary, S. canaria, Serinus canarius, canary
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