close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
IL12BInterleukin-12 subunit beta. (314 aa)    
Predicted Functional Partners:
IFNG
Interferon gamma.
  
  
 0.622
P4HB
Protein disulfide-isomerase A1.
   
  0.547
PDIA2
Protein disulfide-isomerase A2.
   
  0.547
ENSSCAP00000009941
annotation not available
   
 
 0.529
IL10
Interleukin 10.
   
 
 0.520
IL6
Interleukin 6.
     
 0.496
CD86
T-lymphocyte activation antigen CD86.
  
   
 0.494
STAT3
Signal transducer and activator of transcription 3 isoform X2.
   
 
 0.484
IL18
Interleukin-18 isoform X1.
   
 
 0.480
IL1B
Interleukin-1 beta isoform X2.
   
 
 0.452
Your Current Organism:
Serinus canaria
NCBI taxonomy Id: 9135
Other names: Atlantic canary, Canario raza, Common canary, S. canaria, Serinus canarius, canary
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.