STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SPRY4Protein sprouty homolog 4. (297 aa)    
Predicted Functional Partners:
CBL
E3 ubiquitin-protein ligase CBL.
    
 0.759
CBLB
E3 ubiquitin-protein ligase CBL-B isoform X1.
    
 0.759
IL17RD
Interleukin 17 receptor D.
      
 0.533
GRB2
Growth factor receptor-binding protein 2.
    
 0.529
RAF1
RAF proto-oncogene serine/threonine-protein kinase isoform X1.
    
 0.510
GRAP2
GRB2-related adapter protein 2.
    
 0.494
GRAP
GRB2-related adapter protein isoform X1.
    
 0.494
SPRY1
Protein sprouty homolog 1.
   
0.492
TESK1
Testis associated actin remodelling kinase 1.
    
 0.491
BRAF
B-Raf proto-oncogene serine/threonine-protein kinase.
    
 0.486
Your Current Organism:
Serinus canaria
NCBI taxonomy Id: 9135
Other names: Atlantic canary, Canario raza, Common canary, S. canaria, Serinus canarius, canary
Server load: low (34%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.