Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
SPRY4Protein sprouty homolog 4. (297 aa)    
Predicted Functional Partners:
TESK1
Testis associated actin remodelling kinase 1.
    
 0.797
TESK2
Dual specificity testis-specific protein kinase 2.
    
 0.688
IL17RD
Interleukin 17 receptor D.
   
  
 0.686
CBL
E3 ubiquitin-protein ligase CBL.
    
 0.672
CBLB
E3 ubiquitin-protein ligase CBL-B isoform X1.
    
 0.672
FGF8
Fibroblast growth factor 8.
   
  
 0.609
GRB2
Growth factor receptor-binding protein 2.
    
 0.541
DUSP6
Dual specificity protein phosphatase 6.
   
  
 0.540
RAF1
RAF proto-oncogene serine/threonine-protein kinase isoform X1.
    
 0.512
TRIP4
Activating signal cointegrator 1.
      
 0.510
Your Current Organism:
Serinus canaria
NCBI taxonomy Id: 9135
Other names: Atlantic canary, Canario raza, Common canary, S. canaria, Serinus canarius, canary
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