STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MAP4K5Mitogen-activated protein kinase kinase kinase kinase 5 isoform X1. (811 aa)    
Predicted Functional Partners:
CRKL
Proto-oncogene C-crk.
    
 
 0.614
LCP2
Lymphocyte cytosolic protein 2.
    
 
 0.585
CRK
CRK proto-oncogene, adaptor protein.
    
 
 0.584
GRAP2
GRB2-related adapter protein 2.
   
 
 0.579
GRB2
Growth factor receptor-binding protein 2.
   
 
 0.576
RRAGB
Ras-related GTP-binding protein A/B.
    
 
 0.510
NCK2
Cytoplasmic protein NCK2.
    
 
 0.478
MPP5
MAGUK p55 subfamily member 5.
   
 
 0.468
RRAGD
Ras-related GTP-binding protein D isoform X1.
    
 
 0.408
RRAGC
LOW QUALITY PROTEIN: ras-related GTP-binding protein C.
    
 
 0.408
Your Current Organism:
Serinus canaria
NCBI taxonomy Id: 9135
Other names: Atlantic canary, Canario raza, Common canary, S. canaria, Serinus canarius, canary
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.