Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
NF2Merlin isoform X1. (582 aa)    
Predicted Functional Partners:
AMOTL2
Angiomotin like 2.
    
 0.983
AMOT
Angiomotin.
    
 0.976
AMOTL1
LOW QUALITY PROTEIN: angiomotin-like protein 1.
    
 0.971
LATS1
Serine/threonine-protein kinase LATS1 isoform X2.
    
 
 0.920
LATS2
Serine/threonine-protein kinase LATS1/2.
    
 
 0.915
LOC103820087
Merlin-like isoform X1.
  
  
 
0.901
DCAF1
DDB1- and CUL4-associated factor 1.
    
 
 0.863
HGS
Hepatocyte growth factor-regulated tyrosine kinase substrate isoform X1.
    
 
 0.846
SAV1
Protein salvador homolog 1.
    
 
 0.708
DDB1
DNA damage-binding protein 1.
    
   0.673
Your Current Organism:
Serinus canaria
NCBI taxonomy Id: 9135
Other names: Atlantic canary, Canario raza, Common canary, S. canaria, Serinus canarius, canary
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