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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CCNA2Cyclin-A2. (545 aa)    
Predicted Functional Partners:
CDK1
Cyclin-dependent kinase 1.
 
 
 0.999
RB1
Retinoblastoma-associated protein.
   
 0.990
CDC20
Cell division cycle 20, cofactor of APC complex.
   
 0.986
CDKN1B
Cyclin-dependent kinase inhibitor 1B.
    
 0.985
SRSF3
Cyclin-dependent kinase inhibitor 1 isoform X1.
    
 0.985
SKP2
F-box and leucine-rich repeat protein 1 (S-phase kinase-associated protein 2).
   
 0.982
E2F2
Transcription factor E2F2 isoform X3.
   
 0.981
CCNA1
Cyclin-A1.
  
 
0.978
CDC6
Cell division cycle 6.
   
 0.976
UBE2C
Ubiquitin-conjugating enzyme E2 C.
   
 0.973
Your Current Organism:
Serinus canaria
NCBI taxonomy Id: 9135
Other names: Atlantic canary, Canario raza, Common canary, S. canaria, Serinus canarius, canary
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.