Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CCNA2Cyclin-A2. (545 aa)    
Predicted Functional Partners:
CDK1
Cyclin-dependent kinase 1.
   
 0.999
FZR1
Cell division cycle 20-like protein 1, cofactor of APC complex.
   
 0.998
CDC6
Cell division cycle 6.
   
 0.998
RB1
Retinoblastoma-associated protein.
   
 0.998
CDC20
Cell division cycle 20, cofactor of APC complex.
   
 0.997
CCNA1
Cyclin-A1.
  
 
0.993
SKP2
F-box and leucine-rich repeat protein 1 (S-phase kinase-associated protein 2).
   
 0.989
E2F1
E2F transcription factor 1.
   
 0.988
CDT1
Chromatin licensing and DNA replication factor 1.
   
 0.987
UBE2C
Ubiquitin-conjugating enzyme E2 C.
   
 0.987
Your Current Organism:
Serinus canaria
NCBI taxonomy Id: 9135
Other names: Atlantic canary, Canario raza, Common canary, S. canaria, Serinus canarius, canary
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.