Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
MDKMidkine. (199 aa)    
Predicted Functional Partners:
STAT3
Signal transducer and activator of transcription 3 isoform X2.
     
 0.757
PTPRZ1
Receptor-type tyrosine-protein phosphatase zeta isoform X1.
    
 0.729
LTK
Leukocyte tyrosine kinase receptor.
    
 0.726
ALK
ALK receptor tyrosine kinase.
    
 0.726
BRAF
B-Raf proto-oncogene serine/threonine-protein kinase.
    
 0.717
PIK3CA
Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta.
     
 0.695
ROS1
Proto-oncogene tyrosine-protein kinase ROS.
    
 0.686
REM1
LOW QUALITY PROTEIN: GTP-binding protein REM 1.
      
 0.683
ZHX2
Zinc fingers and homeoboxes protein 2.
      
 0.675
MET
Proto-oncogene tyrosine-protein kinase Met.
    
 0.654
Your Current Organism:
Serinus canaria
NCBI taxonomy Id: 9135
Other names: Atlantic canary, Canario raza, Common canary, S. canaria, Serinus canarius, canary
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.