Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
IL1R2Interleukin-1 receptor type 2 isoform X2. (415 aa)    
Predicted Functional Partners:
IL1B
Interleukin-1 beta isoform X2.
   
 0.996
IL1RAP
Interleukin 1 receptor accessory protein.
   
 
 0.896
RAD50
DNA repair protein RAD50.
    
 0.752
EXOC8
Exocyst complex component 8.
    
   0.738
AHSG
Alpha-2-HS-glycoprotein.
    
 0.698
IRAK1BP1
Interleukin-1 receptor-associated kinase 1-binding protein 1.
      
 0.687
VPS35
Vacuolar protein sorting-associated protein 35.
      
 0.682
EXOC2
Exocyst complex component 2.
    
   0.646
FGF19
Fibroblast growth factor 19.
     
 0.641
TUBE1
Tubulin epsilon chain isoform X2.
    
 
 0.639
Your Current Organism:
Serinus canaria
NCBI taxonomy Id: 9135
Other names: Atlantic canary, Canario raza, Common canary, S. canaria, Serinus canarius, canary
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