Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
DIAPH2Diaphanous related formin 2. (1166 aa)    
Predicted Functional Partners:
RHOA
Ras homolog gene family, member A.
   
 0.969
PFN2
Profilin-2 isoform X1.
    
 0.937
CDC42
Cell division control protein 42 homolog isoform X1.
   
 0.841
RND3
LOW QUALITY PROTEIN: rho-related GTP-binding protein RhoE.
   
 0.712
RHOB
Rho-related GTP-binding protein RhoB.
   
 0.712
RHOC
Rho-related GTP-binding protein RhoC isoform X1.
   
 0.712
ANLN
Actin-binding protein anillin.
   
 
 0.705
FMN1
Formin 1.
    
 0.620
ECT2
Protein ECT2 isoform X1.
   
 
 0.615
TDRD3
Tudor domain-containing protein 3 isoform X1.
      
 0.615
Your Current Organism:
Serinus canaria
NCBI taxonomy Id: 9135
Other names: Atlantic canary, Canario raza, Common canary, S. canaria, Serinus canarius, canary
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