Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
STAT4Signal transducer and activator of transcription 4. (749 aa)    
Predicted Functional Partners:
JAK2
Tyrosine-protein kinase JAK2.
   
 0.880
TYK2
Non-receptor tyrosine-protein kinase TYK2.
   
 0.880
ENSSCAP00000008989
Tyrosine-protein kinase JAK1-like.
   
 0.880
ENSSCAP00000009135
annotation not available
   
 0.880
IFNAR2
Interferon alpha/beta receptor 2 isoform X1.
   
 0.838
EP300
Histone acetyltransferase p300.
    
 0.793
SOCS3
Suppressor of cytokine signaling 3.
   
 0.788
EIF2AK2
Interferon-induced, double-stranded RNA-activated protein kinase isoform X1.
   
 0.775
IRF1
Interferon regulatory factor 1.
   
 0.764
FOS
Proto-oncogene protein c-fos.
   
 0.739
Your Current Organism:
Serinus canaria
NCBI taxonomy Id: 9135
Other names: Atlantic canary, Canario raza, Common canary, S. canaria, Serinus canarius, canary
Server load: low (14%) [HD]