Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
ARHGEF6Rho guanine nucleotide exchange factor 6 isoform X1. (770 aa)    
Predicted Functional Partners:
GIT1
GIT ArfGAP 1.
   
 0.985
PAK2
Serine/threonine-protein kinase PAK 2.
   
 0.984
ENSSCAP00000001235
annotation not available
   
 0.966
ENSSCAP00000003249
Probable serine/threonine-protein kinase PIX7 isoform X1.
   
 0.966
RAC2
Ras-related C3 botulinum toxin substrate 2 isoform X1.
   
 0.966
RAC1
Ras-related C3 botulinum toxin substrate 1.
   
 0.966
RAC3
Ras-related C3 botulinum toxin substrate 3.
   
 0.966
LOC103816370
Serine/threonine-protein kinase PAK 3.
   
 0.966
ARHGEF12
Rho guanine nucleotide exchange factor 12 isoform X4.
   
 0.955
PAK4
LOW QUALITY PROTEIN: serine/threonine-protein kinase PAK 4.
    
 0.951
Your Current Organism:
Serinus canaria
NCBI taxonomy Id: 9135
Other names: Atlantic canary, Canario raza, Common canary, S. canaria, Serinus canarius, canary
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