Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PMS1PMS1 protein homolog 1 isoform X1. (933 aa)    
Predicted Functional Partners:
MSH6
DNA mismatch repair protein MSH6.
 
 0.994
MSH2
DNA mismatch repair protein MSH2.
 
 0.993
MLH1
DNA mismatch repair protein Mlh1 isoform X1.
   
0.992
MSH3
DNA mismatch repair protein MSH3.
 
 0.984
EXO1
Exonuclease 1 isoform X1.
   
 0.926
FAN1
Fanconi-associated nuclease 1 isoform X1.
   
 
 0.923
MSH4
MutS protein homolog 4 isoform X3.
 
 0.885
PCNA
Proliferating cell nuclear antigen.
   
 0.872
MSH5
DNA mismatch repair protein MSH5.
  
 0.846
PMS2
Mismatch repair endonuclease PMS2.
  
0.814
Your Current Organism:
Serinus canaria
NCBI taxonomy Id: 9135
Other names: Atlantic canary, Canario raza, Common canary, S. canaria, Serinus canarius, canary
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