Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
DOCK8Dedicator of cytokinesis protein 8 isoform X1. (2050 aa)    
Predicted Functional Partners:
ARPC3
Actin related protein 2/3 complex, subunit 3.
    
 
 0.901
ARID4B
AT-rich interactive domain-containing protein 4B isoform X1.
      
 0.886
CDC42
Cell division control protein 42 homolog isoform X1.
   
 0.869
DOCK7
Dedicator of cytokinesis protein 7 isoform X1.
    
   0.833
RHOJ
Rho-related GTP-binding protein RhoJ.
   
 0.752
RHOQ
Rho-related GTP-binding protein RhoQ isoform X1.
   
 0.752
PIGG
Ethanolamine phosphate transferase 2 subunit G.
      
 0.737
CHRNA6
Neuronal acetylcholine receptor subunit alpha-6.
      
 0.734
LPAR1
Lysophosphatidic acid receptor 1.
      
 0.728
INPP5D
Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1.
   
  
 0.717
Your Current Organism:
Serinus canaria
NCBI taxonomy Id: 9135
Other names: Atlantic canary, Canario raza, Common canary, S. canaria, Serinus canarius, canary
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.