Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
TXN2Thioredoxin, mitochondrial. (409 aa)    
Predicted Functional Partners:
TXNRD2
Thioredoxin reductase 2, mitochondrial.
  
 0.990
PRDX3
Peroxiredoxin 3.
  
 0.980
TXNIP
Thioredoxin interacting protein.
    
 0.979
TXN
Thioredoxin 1.
  
0.960
PRDX1
Peroxiredoxin 1.
  
 0.828
PRDX4
Peroxiredoxin 4.
  
 0.793
TXNRD1
Thioredoxin reductase 1, cytoplasmic isoform X1.
  
 0.789
TXNRD3
Thioredoxin reductase (NADPH).
  
 0.789
MSRA
Mitochondrial peptide methionine sulfoxide reductase isoform X1.
   
 0.769
MAP3K5
Mitogen-activated protein kinase kinase kinase 5.
    
 0.768
Your Current Organism:
Serinus canaria
NCBI taxonomy Id: 9135
Other names: Atlantic canary, Canario raza, Common canary, S. canaria, Serinus canarius, canary
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