Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
WRNWerner syndrome ATP-dependent helicase isoform X2. (1454 aa)    
Predicted Functional Partners:
TOP3A
DNA topoisomerase 3-alpha isoform X1.
  
 0.995
DNA2
DNA replication ATP-dependent helicase/nuclease DNA2.
   
 0.995
FEN1
Flap endonuclease 1.
  
 0.983
ATM
Serine-protein kinase ATM isoform X1.
   
 0.978
RAD52
DNA repair and recombination protein RAD52.
   
 0.978
RPA1
Replication protein A 70 kDa DNA-binding subunit.
   
 0.978
XRCC5
X-ray repair cross-complementing protein 5 isoform X1.
   
 
 0.977
XRCC6
X-ray repair cross-complementing protein 6.
   
 
 0.976
RPA3
Replication protein A 14 kDa subunit.
    
 0.976
PCNA
Proliferating cell nuclear antigen.
  
 0.976
Your Current Organism:
Serinus canaria
NCBI taxonomy Id: 9135
Other names: Atlantic canary, Canario raza, Common canary, S. canaria, Serinus canarius, canary
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