Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
TOLLIPToll-interacting protein isoform X1. (266 aa)    
Predicted Functional Partners:
MYD88
Myeloid differentiation primary response protein MyD88.
   
 0.962
IRAK2
Interleukin-1 receptor-associated kinase-like 2 isoform X1.
    
 0.955
TOM1L1
TOM1-like protein 1.
    
 
 0.950
TLR2
Toll-like receptor 2.
    
 0.940
TRAF6
TNF receptor-associated factor 6.
    
 0.892
IRAK4
Interleukin-1 receptor-associated kinase 4.
    
 0.882
TIRAP
Toll-interleukin 1 receptor (TIR) domain-containing adaptor protein.
     
 0.882
IL1RAP
Interleukin 1 receptor accessory protein.
    
 0.864
TOM1
Target of Myb protein 1 isoform X1.
   
 
 0.838
TOM1L2
TOM1-like protein 2 isoform X2.
   
 
 0.838
Your Current Organism:
Serinus canaria
NCBI taxonomy Id: 9135
Other names: Atlantic canary, Canario raza, Common canary, S. canaria, Serinus canarius, canary
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