Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
MKS1Meckel syndrome type 1 protein. (682 aa)    
Predicted Functional Partners:
B9D1
B9 domain-containing protein 1 isoform X2.
    
 0.997
TMEM67
Meckelin.
     
 0.994
TCTN1
Tectonic-1/3.
    
 0.987
CC2D2A
Coiled-coil and C2 domain containing 2A.
    
 0.981
AHI1
Jouberin.
    
 0.976
TMEM216
Transmembrane protein 216.
     
 0.970
TCTN2
Tectonic-2.
     
 0.927
TMEM231
Transmembrane protein 231 isoform X1.
    
 0.876
CEP290
Centrosomal protein 290.
    
 
 0.776
TMEM17
Transmembrane protein 17.
     
 0.739
Your Current Organism:
Serinus canaria
NCBI taxonomy Id: 9135
Other names: Atlantic canary, Canario raza, Common canary, S. canaria, Serinus canarius, canary
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