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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PLXNB1Plexin-B1 isoform X1. (2203 aa)    
Predicted Functional Partners:
SEMA4D
Semaphorin-4D isoform X1.
    
0.868
ENSSCAP00000019231
annotation not available
    
 0.837
RND3
LOW QUALITY PROTEIN: rho-related GTP-binding protein RhoE.
    
 0.759
MET
Proto-oncogene tyrosine-protein kinase Met.
    
0.719
ARHGEF12
Rho guanine nucleotide exchange factor 12 isoform X4.
    
 0.710
SEMA5A
Semaphorin-5A.
    
0.693
SEMA5B
Semaphorin-5B isoform X1.
    
0.680
NRP1
Neuropilin-1 isoform X1.
    
 0.674
MST1R
Macrophage-stimulating protein receptor isoform X2.
    
0.616
EGFR
Epidermal growth factor receptor isoform X3.
    
 0.616
Your Current Organism:
Serinus canaria
NCBI taxonomy Id: 9135
Other names: Atlantic canary, Canario raza, Common canary, S. canaria, Serinus canarius, canary
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.