Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SETD5Histone-lysine N-methyltransferase SETD5 isoform X1. (1492 aa)    
Predicted Functional Partners:
KMT2E
Inactive histone-lysine N-methyltransferase 2E isoform X1.
   
 
0.864
THUMPD3
THUMP domain-containing protein 3 isoform X1.
      
 0.769
ZMYND11
Zinc finger MYND domain-containing protein 11 isoform X1.
    
 
 0.652
SETD2
[histone H3]-dimethyl-L-lysine36 N-methyltransferase.
   
 
 0.615
BTBD8
AP2-interacting clathrin-endocytosis protein.
   
  
 0.614
PTRH2
Peptidyl-tRNA hydrolase 2, mitochondrial.
      
 0.612
MOSMO
Modulator of smoothened.
      
 0.574
PHF3
PHD finger protein 3 isoform X2.
   
  
 0.568
ENSSCAP00000002502
annotation not available
    
 0.466
ENSSCAP00000023533
annotation not available
    
 0.466
Your Current Organism:
Serinus canaria
NCBI taxonomy Id: 9135
Other names: Atlantic canary, Canario raza, Common canary, S. canaria, Serinus canarius, canary
Server load: low (30%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.