Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
ABCC8ATP-binding cassette subfamily C (CFTR/MRP) member 8. (1473 aa)    
Predicted Functional Partners:
KCNJ11
Potassium inwardly-rectifying channel subfamily J member 11.
   
 0.999
KCNJ8
Potassium inwardly-rectifying channel subfamily J member 8.
   
 0.985
ABCC9
ATP-binding cassette sub-family C member 9 isoform X1.
  
0.797
PRKACB
CAMP-dependent protein kinase catalytic subunit beta isoform X1.
   
 0.687
HNF1A
Transcription factor 1, hepatocyte nuclear factor 1-alpha.
   
  
 0.622
SLC30A8
Solute carrier family 30 (zinc transporter), member 8.
      
 0.607
SLC30A3
Solute carrier family 30 (zinc transporter), member 3.
      
 0.607
SLC2A2
MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 2.
   
 
 0.597
PCSK2
Proprotein convertase subtilisin/kexin type 2.
  
 
 0.552
PCSK1
Proprotein convertase subtilisin/kexin type 1.
  
 
 0.552
Your Current Organism:
Serinus canaria
NCBI taxonomy Id: 9135
Other names: Atlantic canary, Canario raza, Common canary, S. canaria, Serinus canarius, canary
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