GRB10 protein (Serinus canaria) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

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Gene Fusion

Cooccurrence

Coexpression

Experiments

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Textmining

[Homology]

Score

GRB10

Growth factor receptor-bound protein 10 isoform X2. (596 aa)

Predicted Functional Partners:

INSR

0.954

IGF1R

0.954

MTOR

0.902

RET

0.602

PIK3CA

0.598

INS

0.579

GRB2

0.566

INSRR

0.564

TEK

0.552

NRTN

0.517

Your Current Organism:

Serinus canaria

NCBI taxonomy Id: 9135
Other names: Atlantic canary, Canario raza, Common canary, S. canaria, Serinus canarius, canary

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
GRB10	GRB2	ENSSCAP00000007074	ENSSCAP00000001089	Growth factor receptor-bound protein 10 isoform X2.	Growth factor receptor-binding protein 2.	0.566
GRB10	IGF1R	ENSSCAP00000007074	ENSSCAP00000010747	Growth factor receptor-bound protein 10 isoform X2.	Insulin-like growth factor 1 receptor.	0.954
GRB10	INS	ENSSCAP00000007074	ENSSCAP00000005778	Growth factor receptor-bound protein 10 isoform X2.	Insulin.	0.579
GRB10	INSR	ENSSCAP00000007074	ENSSCAP00000004351	Growth factor receptor-bound protein 10 isoform X2.	Insulin receptor.	0.954
GRB10	INSRR	ENSSCAP00000007074	ENSSCAP00000002495	Growth factor receptor-bound protein 10 isoform X2.	Insulin receptor related receptor.	0.564
GRB10	MTOR	ENSSCAP00000007074	ENSSCAP00000003917	Growth factor receptor-bound protein 10 isoform X2.	Serine/threonine-protein kinase mTOR isoform X2.	0.902
GRB10	NRTN	ENSSCAP00000007074	ENSSCAP00000021839	Growth factor receptor-bound protein 10 isoform X2.	Neurturin.	0.517
GRB10	PIK3CA	ENSSCAP00000007074	ENSSCAP00000016929	Growth factor receptor-bound protein 10 isoform X2.	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta.	0.598
GRB10	RET	ENSSCAP00000007074	ENSSCAP00000003521	Growth factor receptor-bound protein 10 isoform X2.	Proto-oncogene tyrosine-protein kinase receptor Ret isoform X2.	0.602
GRB10	TEK	ENSSCAP00000007074	ENSSCAP00000015027	Growth factor receptor-bound protein 10 isoform X2.	TEK receptor tyrosine kinase.	0.552
GRB2	GRB10	ENSSCAP00000001089	ENSSCAP00000007074	Growth factor receptor-binding protein 2.	Growth factor receptor-bound protein 10 isoform X2.	0.566
GRB2	IGF1R	ENSSCAP00000001089	ENSSCAP00000010747	Growth factor receptor-binding protein 2.	Insulin-like growth factor 1 receptor.	0.950
GRB2	INS	ENSSCAP00000001089	ENSSCAP00000005778	Growth factor receptor-binding protein 2.	Insulin.	0.678
GRB2	INSR	ENSSCAP00000001089	ENSSCAP00000004351	Growth factor receptor-binding protein 2.	Insulin receptor.	0.950
GRB2	INSRR	ENSSCAP00000001089	ENSSCAP00000002495	Growth factor receptor-binding protein 2.	Insulin receptor related receptor.	0.527
GRB2	NRTN	ENSSCAP00000001089	ENSSCAP00000021839	Growth factor receptor-binding protein 2.	Neurturin.	0.490
GRB2	PIK3CA	ENSSCAP00000001089	ENSSCAP00000016929	Growth factor receptor-binding protein 2.	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta.	0.678
GRB2	RET	ENSSCAP00000001089	ENSSCAP00000003521	Growth factor receptor-binding protein 2.	Proto-oncogene tyrosine-protein kinase receptor Ret isoform X2.	0.739
GRB2	TEK	ENSSCAP00000001089	ENSSCAP00000015027	Growth factor receptor-binding protein 2.	TEK receptor tyrosine kinase.	0.703
IGF1R	GRB10	ENSSCAP00000010747	ENSSCAP00000007074	Insulin-like growth factor 1 receptor.	Growth factor receptor-bound protein 10 isoform X2.	0.954