Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
MISPMitotic interactor and substrate of PLK1. (317 aa)    
Predicted Functional Partners:
ANLN
Actin-binding protein anillin.
    
   0.716
SAPCD2
Suppressor APC domain containing 2.
      
 0.690
EZR
Ezrin isoform X1.
    
 
 0.537
NUMA1
Nuclear mitotic apparatus protein 1 isoform X1.
      
 0.474
TULP4
TUB like protein 4.
      
 0.470
MASP1
Mannan-binding lectin serine protease 1 isoform X1.
      
 0.470
RIC8A
Synembryn-A.
      
 0.428
MIPEP
Mitochondrial intermediate peptidase.
      
 0.405
Your Current Organism:
Serinus canaria
NCBI taxonomy Id: 9135
Other names: Atlantic canary, Canario raza, Common canary, S. canaria, Serinus canarius, canary
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.