Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
MIS12Kinetochore-associated protein MIS12. (201 aa)    
Predicted Functional Partners:
DSN1
Kinetochore-associated protein DSN1 homolog.
    
 0.998
NSL1
NSL1 component of MIS12 kinetochore complex.
    
 0.997
PMF1
Polyamine-modulated factor 1.
    
 0.994
NDC80
Kinetochore protein NDC80 homolog.
   
 0.992
NUF2
Kinetochore protein Nuf2.
   
 0.989
SPC25
Kinetochore protein Spc25, animal type.
    
 0.987
BUB1B
Uncharacterized protein LOC108964006.
    
 0.978
KNL1
Kinetochore scaffold 1.
   
 0.968
BUB1
BUB1 mitotic checkpoint serine/threonine kinase.
    
 0.962
APOA1
Apolipoprotein A-I.
    
   0.873
Your Current Organism:
Serinus canaria
NCBI taxonomy Id: 9135
Other names: Atlantic canary, Canario raza, Common canary, S. canaria, Serinus canarius, canary
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