Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
USP18Ubiquitin carboxyl-terminal hydrolase 18/41. (388 aa)    
Predicted Functional Partners:
IFNAR2
Interferon alpha/beta receptor 2 isoform X1.
    
 0.995
RSAD2
Radical S-adenosyl methionine domain-containing protein 2.
   
  
 0.961
SKP2
F-box and leucine-rich repeat protein 1 (S-phase kinase-associated protein 2).
    
 
 0.921
MX1
Interferon-induced GTP-binding protein Mx-like.
   
 0.917
DDX58
Probable ATP-dependent RNA helicase DDX58 isoform X1.
   
 
 0.901
MAP3K7
Mitogen-activated protein kinase kinase kinase 7 isoform X5.
    
  0.899
STAT1
Signal transducer and activator of transcription 1-alpha/beta.
   
 0.875
TRIP12
E3 ubiquitin-protein ligase TRIP12 isoform X4.
   
 
 0.846
GGT5
Gamma-glutamyltranspeptidase / glutathione hydrolase / leukotriene-C4 hydrolase.
    
 
 0.834
TAB1
TGF-beta-activated kinase 1 and MAP3K7-binding protein 1.
   
 0.816
Your Current Organism:
Serinus canaria
NCBI taxonomy Id: 9135
Other names: Atlantic canary, Canario raza, Common canary, S. canaria, Serinus canarius, canary
Server load: low (18%) [HD]