STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SH2B2SH2B adapter protein 2 isoform X1. (675 aa)    
Predicted Functional Partners:
CBL
E3 ubiquitin-protein ligase CBL.
    
 0.956
CBLB
E3 ubiquitin-protein ligase CBL-B isoform X1.
    
 0.956
INSR
Insulin receptor.
    
 0.950
JAK2
Tyrosine-protein kinase JAK2.
    
 0.793
GRB2
Growth factor receptor-binding protein 2.
    
0.648
TYK2
Non-receptor tyrosine-protein kinase TYK2.
   
 0.583
ENSSCAP00000008989
Tyrosine-protein kinase JAK1-like.
   
 0.583
ENSSCAP00000009135
annotation not available
   
 0.583
INSRR
Insulin receptor related receptor.
    
 0.527
IGF1R
Insulin-like growth factor 1 receptor.
    
 0.527
Your Current Organism:
Serinus canaria
NCBI taxonomy Id: 9135
Other names: Atlantic canary, Canario raza, Common canary, S. canaria, Serinus canarius, canary
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.