Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
HSPB1Heat shock protein beta-1. (194 aa)    
Predicted Functional Partners:
MAPKAPK2
Mitogen-activated protein kinase-activated protein kinase 2.
    
 0.998
MAPKAPK3
Mitogen-activated protein kinase-activated protein kinase 3.
    
 0.997
MAPKAPK5
Mitogen-activated protein kinase-activated protein kinase 5.
    
 0.997
CRYAB
Alpha-crystallin B chain.
   
 0.947
BAG3
BAG family molecular chaperone regulator 3.
   
 
 0.913
HSPA2
Heat shock-related 70 kDa protein 2.
   
 0.865
HSPA8
Heat shock cognate 71 kDa protein.
   
 0.865
EFTUD2
116 kDa U5 small nuclear ribonucleoprotein component.
    
 
 0.840
SF3B3
Splicing factor 3B subunit 3.
    
   0.832
HNRNPAB
Heterogeneous nuclear ribonucleoprotein A/B isoform X1.
   
 0.804
Your Current Organism:
Serinus canaria
NCBI taxonomy Id: 9135
Other names: Atlantic canary, Canario raza, Common canary, S. canaria, Serinus canarius, canary
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