STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MTHFD1C-1-tetrahydrofolate synthase, cytoplasmic. (935 aa)    
Predicted Functional Partners:
GART
Trifunctional purine biosynthetic protein adenosine-3.
  
 0.998
SHMT1
Serine hydroxymethyltransferase, cytosolic.
  
 0.988
ENSSCAP00000005923
annotation not available
  
 0.987
MTHFD2L
Methylenetetrahydrofolate dehydrogenase(NAD+) / 5,10-methenyltetrahydrofolate cyclohydrolase.
  
0.982
MTHFD2
Methylenetetrahydrofolate dehydrogenase(NAD+) / 5,10-methenyltetrahydrofolate cyclohydrolase.
  
0.982
ATIC
Phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase.
  
 0.979
MTHFR
Methylenetetrahydrofolate reductase isoform X1.
  
 0.973
GLDC
Glycine dehydrogenase (decarboxylating), mitochondrial.
  
 
 0.971
MTR
5-methyltetrahydrofolate--homocysteine methyltransferase.
  
 
 0.970
ENSSCAP00000007279
5-formyltetrahydrofolate cyclo-ligase isoform X1.
   
 0.969
Your Current Organism:
Serinus canaria
NCBI taxonomy Id: 9135
Other names: Atlantic canary, Canario raza, Common canary, S. canaria, Serinus canarius, canary
Server load: medium (58%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.