Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SYVN1LOW QUALITY PROTEIN: E3 ubiquitin-protein ligase synoviolin. (348 aa)    
Predicted Functional Partners:
SEL1L
SEL1L adaptor subunit of ERAD E3 ubiquitin ligase.
   
 0.956
DERL1
Derlin-1.
    
 0.951
ERLEC1
Endoplasmic reticulum lectin 1 isoform X1.
   
 0.905
UBE2J1
Ubiquitin-conjugating enzyme E2 J1.
    
 0.870
UBE2G2
Ubiquitin-conjugating enzyme E2 G2 isoform X1.
    
 
 0.848
HERPUD1
Homocysteine-responsive endoplasmic reticulum-resident ubiquitin-like domain member 1 protein.
   
 0.828
ENSSCAP00000004019
annotation not available
    
 0.823
ENSSCAP00000021652
annotation not available
    
 0.823
DERL3
Derlin-2/3.
   
 0.820
DERL2
Derlin-2/3.
   
 0.820
Your Current Organism:
Serinus canaria
NCBI taxonomy Id: 9135
Other names: Atlantic canary, Canario raza, Common canary, S. canaria, Serinus canarius, canary
Server load: low (16%) [HD]