TRPV4 protein (Serinus canaria) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

TRPV4

Transient receptor potential cation channel subfamily V member 4. (844 aa)

Predicted Functional Partners:

CDC42

0.482

TRPM2

0.458

STIM1

0.458

RHOA

0.440

TRPA1

0.427

TRPC5

0.426

TRPC4

0.424

NT5E

0.420

TLN2

0.420

MYH15

0.420

Your Current Organism:

Serinus canaria

NCBI taxonomy Id: 9135
Other names: Atlantic canary, Canario raza, Common canary, S. canaria, Serinus canarius, canary

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CDC42	RHOA	ENSSCAP00000022849	ENSSCAP00000002532	Cell division control protein 42 homolog isoform X1.	Ras homolog gene family, member A.	0.500
CDC42	STIM1	ENSSCAP00000022849	ENSSCAP00000023551	Cell division control protein 42 homolog isoform X1.	Stromal interaction molecule 1.	0.442
CDC42	TLN2	ENSSCAP00000022849	ENSSCAP00000022872	Cell division control protein 42 homolog isoform X1.	Talin-2 isoform X1.	0.521
CDC42	TRPV4	ENSSCAP00000022849	ENSSCAP00000008169	Cell division control protein 42 homolog isoform X1.	Transient receptor potential cation channel subfamily V member 4.	0.482
MYH15	NT5E	ENSSCAP00000023614	ENSSCAP00000004220	Myosin heavy chain 1/2/3/4/8/13/7B/15.	5'-nucleotidase.	0.685
MYH15	TRPV4	ENSSCAP00000023614	ENSSCAP00000008169	Myosin heavy chain 1/2/3/4/8/13/7B/15.	Transient receptor potential cation channel subfamily V member 4.	0.420
NT5E	MYH15	ENSSCAP00000004220	ENSSCAP00000023614	5'-nucleotidase.	Myosin heavy chain 1/2/3/4/8/13/7B/15.	0.685
NT5E	TRPV4	ENSSCAP00000004220	ENSSCAP00000008169	5'-nucleotidase.	Transient receptor potential cation channel subfamily V member 4.	0.420
RHOA	CDC42	ENSSCAP00000002532	ENSSCAP00000022849	Ras homolog gene family, member A.	Cell division control protein 42 homolog isoform X1.	0.500
RHOA	TLN2	ENSSCAP00000002532	ENSSCAP00000022872	Ras homolog gene family, member A.	Talin-2 isoform X1.	0.517
RHOA	TRPC5	ENSSCAP00000002532	ENSSCAP00000022700	Ras homolog gene family, member A.	Transient receptor potential cation channel subfamily C member 5.	0.426
RHOA	TRPV4	ENSSCAP00000002532	ENSSCAP00000008169	Ras homolog gene family, member A.	Transient receptor potential cation channel subfamily V member 4.	0.440
STIM1	CDC42	ENSSCAP00000023551	ENSSCAP00000022849	Stromal interaction molecule 1.	Cell division control protein 42 homolog isoform X1.	0.442
STIM1	TRPC4	ENSSCAP00000023551	ENSSCAP00000017537	Stromal interaction molecule 1.	Transient receptor potential cation channel subfamily C member 4.	0.682
STIM1	TRPC5	ENSSCAP00000023551	ENSSCAP00000022700	Stromal interaction molecule 1.	Transient receptor potential cation channel subfamily C member 5.	0.571
STIM1	TRPV4	ENSSCAP00000023551	ENSSCAP00000008169	Stromal interaction molecule 1.	Transient receptor potential cation channel subfamily V member 4.	0.458
TLN2	CDC42	ENSSCAP00000022872	ENSSCAP00000022849	Talin-2 isoform X1.	Cell division control protein 42 homolog isoform X1.	0.521
TLN2	RHOA	ENSSCAP00000022872	ENSSCAP00000002532	Talin-2 isoform X1.	Ras homolog gene family, member A.	0.517
TLN2	TRPV4	ENSSCAP00000022872	ENSSCAP00000008169	Talin-2 isoform X1.	Transient receptor potential cation channel subfamily V member 4.	0.420
TRPA1	TRPC4	ENSSCAP00000002367	ENSSCAP00000017537	Transient receptor potential cation channel subfamily A member 1.	Transient receptor potential cation channel subfamily C member 4.	0.437