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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LGR6Leucine-rich repeat-containing G-protein coupled receptor 6 isoform X1. (983 aa)    
Predicted Functional Partners:
RSPO4
R-spondin 4.
    
 0.955
RSPO3
R-spondin 3.
    
 0.938
RSPO2
R-spondin 2.
    
 0.935
RSPO1
R-spondin 1.
    
 0.922
LGR5
Leucine-rich repeat-containing G protein-coupled receptor 5.
  
0.920
LGR4
Leucine-rich repeat-containing G protein-coupled receptor 4.
  
0.919
FSHB
Follitropin subunit beta.
   
 0.648
GPHB5
Glycoprotein hormone beta-5.
     
 0.596
CGA
Glycoprotein hormones alpha chain.
    
 0.573
TSHB
Thyroid stimulating hormone subunit beta.
    
 0.560
Your Current Organism:
Serinus canaria
NCBI taxonomy Id: 9135
Other names: Atlantic canary, Canario raza, Common canary, S. canaria, Serinus canarius, canary
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