STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SDO74102.1Peptidase family M48. (399 aa)    
Predicted Functional Partners:
SDP54997.1
Dynamin family protein.
    
 0.860
SDP29717.1
NnrU protein.
    
 0.582
grpE
Molecular chaperone GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP [...]
  
  
 0.571
SDO74046.1
Sulfinoalanine decarboxylase.
       0.538
SDO74074.1
Hypothetical protein.
       0.529
SDO99207.1
DnaJ like chaperone protein.
  
 
 0.455
SDP37567.1
Hypothetical protein; Belongs to the BI1 family.
  
  
 0.430
SDO62795.1
Curved DNA-binding protein.
  
 
 0.427
SDP04311.1
Curved DNA-binding protein.
  
 
 0.427
dnaJ
Molecular chaperone DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, [...]
  
 
 0.427
Your Current Organism:
Desulforhopalus singaporensis
NCBI taxonomy Id: 91360
Other names: D. singaporensis, DSM 12130, Desulforhopalus singaporensis Lie et al. 2000, strain Spore T1
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.