STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SDP17438.1Succinate dehydrogenase subunit B. (251 aa)    
Predicted Functional Partners:
SDP17408.1
Succinate dehydrogenase subunit A.
 0.999
SDP25970.1
Dissimilatory adenylylsulfate reductase alpha subunit precursor.
  
 0.999
SDP17382.1
Succinate dehydrogenase subunit C.
 
 
 0.996
sucC
succinyl-CoA synthetase (ADP-forming) beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
  
 0.992
SDO75661.1
Fumarase, class I, homodimeric; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.
  
 
 0.991
sucD
succinyl-CoA synthetase (ADP-forming) alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
  
 0.989
SDP67751.1
Pyruvate-ferredoxin/flavodoxin oxidoreductase.
  
 0.981
SDP02988.1
NifU-like protein; May be involved in the formation or repair of [Fe-S] clusters present in iron-sulfur proteins.
  
 0.977
SDO73012.1
Dihydrolipoamide dehydrogenase.
  
 0.967
SDP49535.1
NAD(P)-dependent iron-only hydrogenase diaphorase component flavoprotein.
  
 
 0.960
Your Current Organism:
Desulforhopalus singaporensis
NCBI taxonomy Id: 91360
Other names: D. singaporensis, DSM 12130, Desulforhopalus singaporensis Lie et al. 2000, strain Spore T1
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.