node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SDP29694.1 | SDP50957.1 | SAMN05660330_02330 | SAMN05660330_02986 | Phosphoserine phosphatase. | 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase; Belongs to the HisA/HisF family. | 0.837 |
SDP29694.1 | SDP58903.1 | SAMN05660330_02330 | SAMN05660330_03293 | Phosphoserine phosphatase. | CDP-diacylglycerol---serine O-phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | 0.794 |
SDP29694.1 | SDP67560.1 | SAMN05660330_02330 | SAMN05660330_03636 | Phosphoserine phosphatase. | Serine O-acetyltransferase. | 0.864 |
SDP29694.1 | cysS | SAMN05660330_02330 | SAMN05660330_00237 | Phosphoserine phosphatase. | cysteinyl-tRNA synthetase. | 0.774 |
SDP29694.1 | glyA | SAMN05660330_02330 | SAMN05660330_00220 | Phosphoserine phosphatase. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.880 |
SDP29694.1 | hisB | SAMN05660330_02330 | SAMN05660330_03888 | Phosphoserine phosphatase. | Imidazoleglycerol-phosphate dehydratase. | 0.841 |
SDP29694.1 | hisD | SAMN05660330_02330 | SAMN05660330_00134 | Phosphoserine phosphatase. | Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. | 0.757 |
SDP29694.1 | hisH | SAMN05660330_02330 | SAMN05660330_02004 | Phosphoserine phosphatase. | Glutamine amidotransferase / cyclase; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF; Belongs to the HisA/HisF family. | 0.999 |
SDP29694.1 | hisI | SAMN05660330_02330 | SAMN05660330_01818 | Phosphoserine phosphatase. | phosphoribosyl-AMP cyclohydrolase; Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP. | 0.843 |
SDP29694.1 | serC | SAMN05660330_02330 | SAMN05660330_01986 | Phosphoserine phosphatase. | Phosphoserine aminotransferase apoenzyme; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily. | 0.918 |
SDP50957.1 | SDP29694.1 | SAMN05660330_02986 | SAMN05660330_02330 | 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase; Belongs to the HisA/HisF family. | Phosphoserine phosphatase. | 0.837 |
SDP50957.1 | hisB | SAMN05660330_02986 | SAMN05660330_03888 | 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase; Belongs to the HisA/HisF family. | Imidazoleglycerol-phosphate dehydratase. | 0.940 |
SDP50957.1 | hisD | SAMN05660330_02986 | SAMN05660330_00134 | 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase; Belongs to the HisA/HisF family. | Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. | 0.955 |
SDP50957.1 | hisH | SAMN05660330_02986 | SAMN05660330_02004 | 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase; Belongs to the HisA/HisF family. | Glutamine amidotransferase / cyclase; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF; Belongs to the HisA/HisF family. | 0.999 |
SDP50957.1 | hisI | SAMN05660330_02986 | SAMN05660330_01818 | 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase; Belongs to the HisA/HisF family. | phosphoribosyl-AMP cyclohydrolase; Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP. | 0.989 |
SDP58903.1 | SDP29694.1 | SAMN05660330_03293 | SAMN05660330_02330 | CDP-diacylglycerol---serine O-phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | Phosphoserine phosphatase. | 0.794 |
SDP58903.1 | SDP67560.1 | SAMN05660330_03293 | SAMN05660330_03636 | CDP-diacylglycerol---serine O-phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | Serine O-acetyltransferase. | 0.744 |
SDP58903.1 | cysS | SAMN05660330_03293 | SAMN05660330_00237 | CDP-diacylglycerol---serine O-phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | cysteinyl-tRNA synthetase. | 0.884 |
SDP58903.1 | glyA | SAMN05660330_03293 | SAMN05660330_00220 | CDP-diacylglycerol---serine O-phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.695 |
SDP67560.1 | SDP29694.1 | SAMN05660330_03636 | SAMN05660330_02330 | Serine O-acetyltransferase. | Phosphoserine phosphatase. | 0.864 |