STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
metXAHomoserine O-acetyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine. (379 aa)    
Predicted Functional Partners:
SDP67573.1
Methionine biosynthesis protein MetW.
  
 0.998
SDP67597.1
O-acetylhomoserine sulfhydrylase.
 
 0.995
SDO50718.1
Homoserine dehydrogenase.
 
 
 0.967
SDP47189.1
O-acetylhomoserine (thiol)-lyase.
 
 0.910
SDP67560.1
Serine O-acetyltransferase.
    
 0.899
SDP67544.1
Cysteine synthase.
    
 0.850
glyA
Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
    
 0.816
SDP59402.1
Cystathionine beta-lyase.
 
  
 0.801
trpB
Tryptophan synthase, beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.
     
 0.798
SDO65366.1
5-methyltetrahydrofolate--homocysteine methyltransferase.
  
 
 0.736
Your Current Organism:
Desulforhopalus singaporensis
NCBI taxonomy Id: 91360
Other names: D. singaporensis, DSM 12130, Desulforhopalus singaporensis Lie et al. 2000, strain Spore T1
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