STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EDX85396.1Conserved TM helix family; [M] COG0668 Small-conductance mechanosensitive channel. (599 aa)    
Predicted Functional Partners:
S7335_310
ABC transporter, ATP-binding protein; [E] COG0410 ABC-type branched-chain amino acid transport systems, ATPase component; Belongs to the binding-protein-dependent transport system permease family.
    
  0.631
EDX86909.1
Hypothetical protein; [K] COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit.
  
     0.517
EDX87100.1
Hypothetical protein.
  
     0.500
EDX83898.1
Bacterial pre-peptidase C-terminal domain family; [K] COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit.
  
    0.466
EDX86492.1
[S] COG1434 Uncharacterized conserved protein.
  
     0.443
gyrA
DNA gyrase, A subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
       0.440
EDX86593.1
Hypothetical protein; [K] COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit.
       0.429
EDX85721.1
Hypothetical protein; [K] COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit.
  
     0.411
Your Current Organism:
Synechococcus sp. PCC7335
NCBI taxonomy Id: 91464
Other names: Coccusdissimilis mexicanus PCC 7335, S. sp. PCC 7335, Synechococcus PCC 7335, Synechococcus PCC7335, Synechococcus mexicanus PCC 7335, Synechococcus sp. PCC 7335
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