STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EDX86922.1Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. (1195 aa)    
Predicted Functional Partners:
EDX86695.1
[E] COG0685 5,10-methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family.
 
 
 0.999
S7335_573
Nitric oxide synthase, oxygenase domain protein; [P] COG0369 Sulfite reductase, alpha subunit (flavoprotein).
  
 0.957
ahcY
Adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.
  
 
 0.952
EDX85692.1
Homoserine dehydrogenase, NAD binding domain family; [E] COG0460 Homoserine dehydrogenase.
  
 
 0.939
gcvT
Glycine cleavage system T protein; The glycine cleavage system catalyzes the degradation of glycine.
  
 
 0.932
EDX84216.1
Hydrolase, alpha/beta fold family, putative; [E] COG2021 Homoserine acetyltransferase; Belongs to the AB hydrolase superfamily. MetX family.
  
 
 0.931
EDX87845.1
[R] COG0656 Aldo/keto reductases, related to diketogulonate reductase.
   
 0.928
EDX87823.1
Asparate kinase, monofunctional class, putative; [E] COG0527 Aspartokinases.
  
 
 0.915
EDX84050.1
Hypothetical protein; [K] COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit.
    
 0.904
mtnA
Methylthioribose-1-phosphate isomerase; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).
  
  
 0.902
Your Current Organism:
Synechococcus sp. PCC7335
NCBI taxonomy Id: 91464
Other names: Coccusdissimilis mexicanus PCC 7335, S. sp. PCC 7335, Synechococcus PCC 7335, Synechococcus PCC7335, Synechococcus mexicanus PCC 7335, Synechococcus sp. PCC 7335
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