STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EDX87721.1Plasmid pRiA4b ORF-3-like protein; [K] COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit. (183 aa)    
Predicted Functional Partners:
secY
Preprotein translocase, SecY subunit; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.
   
 0.951
EDX86975.1
Preprotein translocase, SecG subunit; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family.
    
 0.945
secE
Preprotein translocase, SecE subunit, putative; Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.
    
 0.937
EDX86329.1
KR domain family; [Q] COG3321 Polyketide synthase modules and related proteins.
    
 
 0.887
EDX85110.1
Alkaline phosphatase family protein, putative; [Q] COG2931 RTX toxins and related Ca2+-binding proteins; Belongs to the alkaline phosphatase family.
   
 
 0.847
EDX87604.1
[C] COG0584 Glycerophosphoryl diester phosphodiesterase.
   
 
 0.847
rplW
Ribosomal protein L23; One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome; Belongs to the universal ribosomal protein uL23 family.
    
   0.839
rpmC
[J] COG0255 Ribosomal protein L29; Belongs to the universal ribosomal protein uL29 family.
    
   0.838
polA
DNA polymerase I superfamily; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
  
  
 0.838
rplY
Ribosomal protein L25, Ctc-form; This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance. Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
   
 
 0.780
Your Current Organism:
Synechococcus sp. PCC7335
NCBI taxonomy Id: 91464
Other names: Coccusdissimilis mexicanus PCC 7335, S. sp. PCC 7335, Synechococcus PCC 7335, Synechococcus PCC7335, Synechococcus mexicanus PCC 7335, Synechococcus sp. PCC 7335
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