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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PRDM1PR domain zinc finger protein 1 isoform X1. (813 aa)    
Predicted Functional Partners:
ENSPMJP00000009426
annotation not available
     
 0.692
ROBO1
Roundabout, axon guidance receptor 1.
      
 0.690
GBE1
1,4-alpha-glucan-branching enzyme isoform X1.
      
 0.690
EHMT1
Histone-lysine N-methyltransferase EHMT1 isoform X1.
    
 0.630
STAT3
Signal transducer and activator of transcription 3 isoform X1.
   
 
 0.618
PUF60
Poly(U)-binding-splicing factor PUF60 isoform X1.
      
 0.548
XBP1
LOW QUALITY PROTEIN: X-box-binding protein 1.
   
  
 0.543
BRCA2
Breast cancer type 2 susceptibility protein isoform X1.
      
 0.533
RECK
Reversion-inducing cysteine-rich protein with Kazal motifs isoform X1.
      
 0.487
CIZ1
Cip1-interacting zinc finger protein isoform X1.
   
 
 0.470
Your Current Organism:
Parus major
NCBI taxonomy Id: 9157
Other names: Great Tit, Kohlmeise, P. major
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.